Table 3.
Central hemodynamics and forearm circulation data
| Variable | Control Subjects | ESRD Patients | P Value |
|---|---|---|---|
| n | 73 | 156 | |
| Left ventricular outflow tract area (cm2) | 1.91±0.03 | 1.78±0.03 | <0.001 |
| Left ventricular outflow velocity integral (cm) | 21.8±0.55 | 26.8±0.53 | <0.001 |
| Heart period (ms) | 951±16.2 | 890±11.3 | <0.001 |
| Stroke volume (ml) | 62.1±1.9 | 63.8±1.9 | NS |
| Cardiac output (L/min) | 3.92±0.13 | 4.41±0.14 | 0.03 |
| Aortic peak flow velocity (cm/s) | 108±2.4 | 129±2.4 | <0.001 |
| Aortic peak flow (ml/s) | 309±9.5 | 305±8.5 | NS |
| Characteristic impedance (dyne s per cm−5) | 178±6.7 | 218±8.9 | <0.01 |
| Peripheral resistance (dyne s per cm−5) | 2289±65 | 2143±83 | NS |
| Global reflection coefficient | 0.82±0.06 | 0.76±0.10 | <0.001 |
| n | 36 | 64 | |
| Baseline forearm blood flow (ml/100 ml per min) | 3.6±0.25 | 4.0±0.17 | NS |
| Post-ischemic maximal blood flow (% from baseline) | 816±58 | 573±35 | <0.001 |
| Minimal forearm flow resistance (arbitrary units) | 4.0±0.24 | 4.9±0.27 | 0.01 |
| Forearm flow debt repayment (%) | 119±4.6 | 87±3.8 | <0.001 |
| Duration of vasodilation (s) | 127±4.8 | 97±4.2 | <0.001 |
Values are means±SEMs.