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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Endod. 2016 Apr 23;42(6):935–942. doi: 10.1016/j.joen.2016.03.016

Table 4.

Measures of validity for each diagnostic test by subgroup characteristic

Characteristic Non-response to cold Pain on percussion
N SN, % (95% CI) SP, % (95 % CI) N SN, % (95% CI) SP, % (95 % CI)
Demographic
Age < 50 years 354 85 (78–91) 85 (79–89) 357 76 (69–83) 39 (33–46)
≥ 50 years 347 92 (87–95) 72 (64–79) 349 68 (61–74) 44 (36–53)
Gender Male 287 93 (88–96) 70 (61–78) 289 69 (61–76) 42 (34–51)
Female 405 85 (79–90) 85 (79–89) 408 74 (67–80) 40 (33–46)
Socio-economic status (household income) < $50,000 239 87 (80–93) 81 (73–88) 243 71 (62–79) 44 (34–53)
≥ $50,000 430 90 (85–94) 80 (74–85) 431 74 (67–79) 38 (32–44)
Race/ethnicity White non-Hispanic/Latino 600 88 (84–92) 80 (75–84) 602 70 (65–75) 42 (36–47)
Other 84 92 (78–98) 79 (64–89) 86 84 (69–94) 38 (24–53)
Patient/tooth related
Tooth type Posterior tooth 625 88 (83–91) 79 (75–84) 630 74 (68–78) 42 (36–47)
Anterior tooth 77 96 (88–100) 82 (60–95) 77 62 (48–75) 36 (17–59)
Tooth position Upper jaw 411 89 (84–92) 83 (77–88) 416 72 (65–77) 40 (33–47)
Lower jaw 291 90 (83–94) 75 (68–82) 291 72 (63–80) 43 (36–51)
Preoperative tooth paina Pain 500 85 (79–89) 82 (77–86) 505 85 (79–89) 33 (28–39)
No pain 183 97 (92–99) 70 (58–81) 183 47 (38–56) 78 (66–88)
Medications for tooth pain Intake 410 85 (79–90) 80 (74–85) 415 86 (80–90) 34 (28–40)
No intake 275 93 (88–97) 77 (69–84) 275 55 (46–63) 55 (45–64)
Persistent tooth painb Pain 137 83 (71–92) 83 (73–91) 139 88 (77–95) 33 (23–44)
No pain 555 90 (86–93) 78 (73–83) 558 68 (62–73) 43 (37–49)
Chronic wide-spread pain Wide-spread pain 201 86 (77–92) 78 (68–85) 205 78 (69–86) 34 (25–44)
No wide-spread pain 491 90 (86–94) 80 (74–85) 492 69 (62–74) 43 (37–50)
Fearfulness of dental appointment Fearful 446 88 (83–92) 82 (76–86) 451 74 (67–79) 40 (33–46)
Not fearful 251 91 (85–95) 75 (66–82) 251 69 (61–77) 44 (35–54)
Expectations of RCT outcome Fair to good 244 87 (80–93) 85 (78–91) 247 73 (63–80) 39 (30–48)
Very good 454 90 (85–93) 76 (70–82) 456 72 (65–77) 42 (36–49)
Dentist-related
Dentist training level General practitioner 292 86 (79–91) 66 (57–73) 294 75 (67–82) 36 (28–44)
Endodontist 410 91 (86–95) 89 (84–93) 413 69 (62–76) 45 (38–52)
Overall 702 89 (85–92) 80 (75–84) 707 72 (67–76) 41 (36–47)

The effect of patient- and tooth-related factors and dentist education level on sensitivity (SN) and specificity (SP) for non-response on cold testing and pain on tooth percussion. The reference standard was absence of bleeding within the pulp chamber, prevalence 49%. N= number of patients per group.

Significant between-group difference at the 5% level were marked bold.

a

Preoperative tooth pain was defined as pain with intensity >0 (0–10 scale) for ≥1 days in the preceding week

b

Persistent tooth pain was defined as preoperative pain present for >8h/day, >15 days/month and >3 months