Fig. 7.
Testes pathology in Ap1g1fgt mutant mice. PAS-stained cross sections of testes from a 3-month-old +/fgt control (a) and an age-matched fgt/fgt mutant mouse (b) reveal striking differences in the histological structure of the seminiferous epithelium. Compared with controls, mutant tubules show a disorganized arrangement of sperm cells and Sertoli cells and contain fewer elongated spermatids (darkly stained cells bordering the lumen). A and B are the same magnification; the black scale bar in B represents 20 micrometers