Fig. 4.
TH-IR cell counts at the individual levels A–D and total cell counts over the entire SNc (a, b) and VTA (c, d) of male (a, c) and female (b, d) mice in adulthood following antenatal treatment with dexamethasone via the maternal drinking water on embryonic days 16–19 (grey bars lower dose antenatal GC treatment, AGTL, 0.5 µg/ml; black bars higher dose antenatal GC treatment, AGTH, 1.0 µg/ml) compared to the control offspring of dams receiving normal drinking water (open bars). Data are mean ± SEM, n = 6 animals per treatment group. Up filled triangle, down filled triangle dexamethasone treatment had a significant effect, p < 0.05, to increase or decrease cell counts, respectively, compared with control animals; plus a significant sex difference, p < 0.05 vs. males in the same treatment group