Table 2.
Studies about renal damage and kidney stone and N. sativa L. treatment
| Model | species | Type of extract | Reference/ year |
|---|---|---|---|
| Kidney stone | Rat | Ethanolic | ( Hadjzadeh et al., 2007) |
| Kidney stone | Rat | Ethyl acetate phase remnant fraction | ( Khajavi Rad et al., 2008) |
| Kidney stone | Rat | Thymoquinone | ( Hadjzadeh et al., 2008) |
| Kidney stone | Rat | N-butanol fraction of 50% aqueous ethanolic | ( Hadjzadeh et al., 2011). |
| Renal failure | Rat | Thymoquinone | (Sayed-Ahmed & Nagi, 2007) |
| Hypertension & renal damage | Rat | Thymoquinone | (Khattab & Nagi, 2007) |
| Ischaemia/reperfusion renal injury | Rat | Nigella sativa oil | (Bayrak et al., 2008) |
| Ischaemia/reperfusion renal injury | Rat | Thymoquinone | (Awad et al., 2011) |
| Cisplatin- induced Kidney injury | Rat | Thymoquinone | (Ulu et al., 2012) |
| Bromobenzene hepato-renal toxicity | Rat | Nigella sativa seed oil | (Hamed et al., 2013) |
| Acetaminophen-induced renal impairment | Rat | Nigella sativa oil | (Ahmed, 2013) |
| Ischaemia/reperfusion kidney damage | Rat | Hydroalcoholic extract | (Havakhah et al., 2014) |
| ------ | Kidney tubule epithelial cells | Thymoquinone | (Vance et al., 2008) |