Table 2.
Effect of N. sativa seed extract on average serum levels of cholesterol and triglyceride (mg/dl) in streptozotocin-induced diabetic rats
| Group |
|
Cholesterol
|
|
|
|
Triglyceride
|
|||
|---|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 24 | Day 45 | Day 0 | Day 24 | Day 45 | ||||
| C | 71.91±2.83 | 73.66±1.21 | 72.63±4.17 | 55.42±2.58 | 87.38±4.31 | 56.43±2.44 | |||
| D | 76.05±1.29 | 108.62±1.7*** | 121.42±6.66*** | 61.91 ±6.40 | 293.39±7.82*** | 101.34±2.96*** | |||
| DM | 73±2.23 | 89.38±3.63### | 82.27±3.23### | 64.80±6.4 | 278.99±26.11*** | 267.60±21.31*** | |||
| DE 100 | 70.07±3.79 | 87.43±4.22# | 78.87±2.84### | 65.03±5.56 | 248.56±13.15*** | 60.48±5.21### | |||
| DE 200 | 71.54±2.05 | 87.55±2.16### | 86.25±3.22### | 56.54±2.49 | 190.99±21.28*# | 68.41±5.03### | |||
| DE 400 | 67.08±2.25 | 84.45±6.01### | 80.60±5.60### | 63.05±4.44 | 258.74±28.72*** | 65.82±17.28### | |||
Abbreviations: C: control, D: diabetic, DM: diabetic + metformin, DE 100: diabetic + N. sativa extract of 100 mg/kg, DE 200: diabetic + N. sativa extract of 200 mg/kg, DE 400: diabetic + N. sativa extract of 400 mg/kg. Values are presented as means±SEM (n = 8).
p<0.05,
p<0.001 compared to control group and
p<0.05,
p<0.001 compared to diabetic group.