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Upregulation of Wnt activity in NaB-treated CRC cells occurs by both an increase in the percent cells with Wnt activity and the levels of Wnt activity per cell.
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No NaB | NaB | NaB/No NaB | ||||||
| Cell line | T/F | % W | T/F/W | T/F | %W | T/F/W | ΔT/F | Δ%W | ΔT/F/W |
| HCT-116 | 4.8 | 9.8 | 0.49 | 104.6 | 46.0 | 2.3 | 21.8 | 4.7 | 4.7 |
| DLD-1 | 6.2 | 10.0 | 0.62 | 95.5 | 20.5 | 4.7 | 15.4 | 2.1 | 7.6 |
| LS174T | 14.5 | 19.8 | 0.73 | 193.6 | 40.4 | 4.8 | 13.3 | 2.0 | 6.6 |
| LoVo | 5.7 | 11.7 | 0.49 | 17.9 | 16.5 | 1.1 | 3.2 | 1.4 | 2.2 |
| SW48 | 14.7 | 26.4 | 0.56 | 32.7 | 34.6 | 0.95 | 2.2 | 1.3 | 1.7 |
