Table 3. The Effect of Oral Administration of Metformin, Acarbose, and Their Combination on Serum Visfatin and Insulin Levels in Normal and Nicotinamide/Streptozotocin-induced Type 2 Diabetic Rats^a,b.

Groups	Visfatin, ng	Insulin, µg
Normal	154.4 ± 11.9c	0. 75 ± 0.1c
Diabetic control	195.6 ± 6.4d	0.37 ± 0.07d
Diabetic + metformin	162.7 ± 21.2c	0.31 ± 0.12d
Diabetic + acarbose	183.5 ± 11.3d	0.22 ± 0.014d,c
Diabetic + metformin and acarbose	180.1 ± 5.1d	0.24 ± 0.013d,c

^aEach value is mean ± SD of the six rats in each group.

^bVisfatin: The diabetic control group compared with the normal group (P = 0.0001), the diabetic control group compared with the metformin-treated group (P = 0.001), and the metformin-treated group compared with the acarbose-treated group (P = 0.047) Insulin: The diabetic control group compared with the normal group (P = 0.0001), the diabetic control group compared with the acarbose-treated group (P = 0.020), the diabetic control group compared with the two-drug combination group (P = 0.037), and the normal group compared with all groups (P = 0.0001).

^cP < 0.05 in comparison with diabetic rats.

^dP < 0.05 compared with normal rats.