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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Neurocrit Care. 2016 Jun;24(3):342–352. doi: 10.1007/s12028-015-0216-8

Figure 2. Longitudinal Fractional Anisotropy Changes within White Matter Tracts Affected by Traumatic Axonal Injury.

Figure 2

A traumatic axonal injury (TAI) lesion in the splenium of the corpus callosum of patient 6 (top row) demonstrates FA recovery, as defined by a longitudinal increase in FA that exceeds the coefficient of variation for FA within the splenium of the corpus callosum in the two control datasets. A splenium TAI lesion for patient 7 undergoes a longitudinal decline in FA (bottom row). Each TAI lesion is rendered in 3-dimensions as a semi-transparent white region of interest so that tracts can be visualized passing through the lesions. Fiber tracts were generated using the lesions as seeds. Tracts are color-coded using mean tract FA as a scalar (right panels). All tracts were reconstructed using Diffusion Toolkit version 0.6.2 and TrackVis version 5.2 (Wang & Wedeen, Athinoula A. Martinos Center for Biomedical Imaging, www.trackvis.org).