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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Neurocrit Care. 2016 Jun;24(3):342–352. doi: 10.1007/s12028-015-0216-8

Table 1.

Clinical and Longitudinal Imaging Data.

Pt # Age/ Sex TBI Mechanism GCS DTI Scan Days DWI FLAIR GRE FA ADC (x10−3 mm2/s) AD (x10−3 mm2/s) RD (x10−3 mm2/s) Days to RH D/C DRS at RH D/C
SPLENIUM
1 57M Bicyclist hit by car 10 5 + − − 0.70 0.62 1.24 0.31 63 2.5
14 − − − 0.65 0.72 1.35 0.40
2 21M MVA 6T 2 + + − 0.61 0.49 0.86 0.30 241 11
13 + + − 0.42 0.84 1.27 0.63
26 + + + 0.44 0.90 1.34 0.68
3 31F MVA 7T 1 − − − 0.55 0.94 1.57 0.63 45 3.5
6 + + + 0.52 0.75 1.24 0.51
19 − + N/A 0.57 1.31 2.17 0.88
4 16F Pedestrian hit by car 6T 2 + + − 0.67 0.54 1.02 0.31 102 4.5
11 + + − 0.61 0.56 0.98 0.36
78 − − − 0.60 0.75 1.33 0.45
5 20M MVA 7T 7 + + − 0.58 0.55 0.94 0.36 31 1
15 + + − 0.64 0.67 1.24 0.38
6 17M MVA 3 2 + + + 0.28 0.95 1.24 0.81 178 23
19 − + N/A 0.60 0.79 1.44 0.47
31 − + N/A 0.50 0.85 1.39 0.58
48 − − N/A 0.57 0.90 1.57 0.57
88 − − + 0.52 0.81 1.32 0.56
7 63M Fall 15 feet from roof 15 5 + + − 0.51 0.71 1.13 0.50 108 8.5
32 + + + 0.36 1.04 1.42 0.85
38 + + + 0.39 1.03 1.49 0.79
BODY
3 31F MVA 7T 1 − + − 0.43 0.98 1.47 0.73 45 3.5
6 + + + 0.32 0.68 0.91 0.56
19 − + N/A 0.24 1.46 1.80 1.29
4 16F Pedestrian hit by car 6T 2 + − − 0.33 0.82 1.09 0.69 102 4.5
11 + + + 0.41 1.02 1.51 0.77
78 − − + 0.17 1.28 1.52 1.16
GENU
4 16F Pedestrian hit by car 6T 2 − − + 0.64 0.68 1.31 0.40 102 4.5
11 + + + 0.62 0.61 1.07 0.40
78 − − + 0.53 0.78 1.30 0.52
7 3M Fall 15 feet from roof 15 5 + + − 0.40 0.83 1.16 0.67 108 8.5
32 + − − N/A N/A N/A N/A
38 + − − 0.35 0.94 1.27 0.77

The shaded rows indicate traumatic axonal injury lesions in which axons recovered, as defined by a longitudinal increase in fractional anisotropy (FA) that exceeded the coefficient of variation for FA within the corpus callosum in healthy controls. Abbreviations: “+” indicates that a lesion was visible; “−“ indicates that a lesion was not visible; AD = axial diffusivity; ADC = apparent diffusion coefficient; DRS = Disability Rating Scale score; DWI = diffusion-weighted imaging; FLAIR = T2-weighed fluid-attenuated inversion recovery sequence; GCS = admission Glasgow Coma Scale score; GRE = T2*-weighted gradient-recalled echo sequence; MVA = motor vehicle accident; Pt = patient; RD = radial diffusivity; RH = rehabilitation hospital.