Table 1.
Functional stage | tRNA(s)1 | Other ligands | Head2 | Rotation2 | Organism | Access code3 | Resolution (Å) |
Reference |
---|---|---|---|---|---|---|---|---|
Pre-peptidyl transfer | A/A, P/P, E/E |
- | 0 | 0 | T. thermophilus | 2WDK, 2WDL | 3.5 | Voorhees et al. 2009 |
Decoding | A/T, P/P, E/E |
EF-Tu, GDP, kirromycin, paromomycin |
0 | 0 | T. thermophilus | 2WRN, 2WRO | 3.6 | Schmeing et al. 2009 |
Decoding | A/T, P/P, E/E |
EF-Tu, GDP, kirromycin | 0 | 0 | E. coli | EMD-2847 | 2.9 | Fischer et al. 2015 |
Translocation | P/E | EF-G•GDPCP | 6.5 | 6.3 | T. thermophilus | 4JUW, 4JUX | 2.9 | Tourigny et al. 2013 |
Post-termination | P/E | RF3•GDPCP | 6 | 8.8 | T. thermophilus | 3ZVO, 3ZVP | 3.8 | Jin et al. 2011 |
Post-termination | - | RF3•GDPNP | 16.3 | 6.8 | E. coli | 3SFS, 3SGF | 3.2 | Zhou et al. 2012 |
Post-termination | P/P | - | 1.5 | −1.2 | E. coli | 3R8O, 3R8T | 3.2 | Dunkle et al. 2011 |
Recycling | P/E | RRF | 4.8 | 8.4 | E. coli | 3R8N, 3R8S | 3.2 | Dunkle et al. 2011 |
Each bound tRNA is listed in its classical or hybrid configuration.
Degrees of head swiveling (Head) and intersubunit rotation (Rotation) are obtained from Mohan et al. 2014.
Access codes are for PDB (crystal structures) or EMDB (cryo-EM reconstructions) entries.