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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Mutat Res Rev Mutat Res. 2016 Mar 31;768:27–45. doi: 10.1016/j.mrrev.2016.03.004

Table 3.

Number of publications concerning epigenetics for each chemical or related occupation included in the systematic literature review.

DNA methylation Histone modification Non-coding RNA
Human
(Homo
sapiens)
Mouse
(Mus
musculus)
Rat
(Rattus
norvegicus)
Other
(see
footnotes)
Human
(Homo
sapiens)
Mouse
(Mus
musculus)
Rat
(Rattus
norvegicus)
Other
(see
footnotes)
Human
(Homo
sapiens)
Mouse
(Mus
musculus)
Rat
(Rattus
norvegicus)
Other
(see
footnotes)
Total
Benzo[a]pyrene in
vitro
11 6 3*, 1 6 2 1 16 3 48
in
vivo
5 4 3§, 2#, 1 1 1 7 1 25
Aflatoxins (naturally
occurring mixtures)
in
vitro
1 1*, 1& 1& 7 1 12
in
vivo
10 2 1 1 1 1 3 2 21
Benzene in
vitro
5 1 1 1 8
in
vivo
9 1 1 1 1 3 2 18
Formaldehyde in
vitro
1 2 1© 1 5
in
vivo
2 1 1$ 4
Coke production,
occupational
exposures
in
vitro
0
in
vivo
6 2 8
1,3-Butadiene in
vitro
0
in
vivo
3 3 6
Sulfur mustard in
vitro
1 1 2
in
vivo
3 1 4
Vinyl chloride in
vitro
0
in
vivo
3 3
4-Aminobiphenyl in
vitro
1 1 2
in
vivo
0
Benzidine in
vitro
0
in
vivo
1 1
4,4'-Methylenebis(2-
chlorobenzenamine)
in
vitro
1 1
in
vivo
0
Occupational
exposure as a painter
in
vitro
0
in
vivo
1 1
*

Oligodeoxynucleotides

Hamster (Mesocricetus auratus)

Frog (Xenopus borealis)

§

Zebrafish (Danio rerio)

#

Mummichog fish (Fundulus heteroclitus)

&

Pig (Sus domesticus)

Rainbow trout (Oncorhynchus mykiss)

©

Synthetic peptide

$

Cynomolgus macaques (Macaca fascicularis)