Table 2.
CACI Outcomes and Univariate Association of Age Comorbidities and 1-Year Mortality
| 1 Year After Salvage Surgery |
||||
|---|---|---|---|---|
| Comorbidity | Weight for CACI Calculation | No. (%) of Patients (N = 191) | 1-Year Mortality Rate, No. (%) | RR of Mortality Within 1 Year of Salvage Surgery (95% CI) |
| Myocardial infarction | 1 | 19 (9.9) | 6 (31.6) | 1.12 (0.55-2.26) |
| Congestive heart failure | 1 | 12 (6.3) | 6 (50) | 1.84 (0.99-3.41) |
| Peripheral vascular disease | 1 | 19 (9.9) | 4 (21) | 0.71 (0.29-1.76) |
| Stroke | 1 | 7 (3.7) | 2 (29) | 0.99 (0.30-3.29) |
| Dementia | 1 | 2 (1.0) | 1 (50) | 1.76 (0.43-7.17) |
| Pulmonary | 1 | 50 (26.2) | 16 (32) | 1.17 (0.72-1.90) |
| Rheumatic disease | 1 | 5 (2.6) | 4 (80) | 2.93 (1.78-4.84)a |
| Peptic ulcer disease | 1 | 2 (1.0) | ... | ... |
| Liver disease, mild | 1 | 6 (3.1) | 3 (50) | 1.79 (0.77-4.12) |
| Diabetes mellitus | 1 | 30 (15.7) | 11 (37) | 1.35 (0.79-2.31) |
| Diabetes with end-organ damage | 2 | 5 (2.6) | 2 (40) | 1.41 (0.47-4.23) |
| Paralysis | 2 | 1 (0.5) | ... | ... |
| Renal disease | 2 | 6 (3.1) | 3 (50) | 1.79 (0.78-4.12) |
| Any tumor | 2 | 191 (100) | ... | ... |
| Liver disease, severe | 3 | 1 (0.5) | 1 (100) | 3.52 (2.81-4.45)a |
| Metastasisb | 4 | 45 (23.6) | 25 (56) | 2.78 (1.82-4.24)a |
| Human Immunodeficiency virus infection | 6 | 0 | ... | ... |
| Age, y | ||||
| 0-49 | ... | 21 (11.0) | 4 (8) | 1.22 (0.98-1.51)a |
| 50-59 | ... | 19 (9.9) | 0 (0) | |
| 60-69 | ... | 49 (25.7) | 13 (24) | |
| 70-79 | ... | 67 (35.1) | 16 (30) | |
| 80-89 | ... | 45 (23.6) | 18 (44) | |
| 90-99 | ... | 9 (4.7) | 2 (4) | |
| Total comorbidity score, OR (95% CI) | ... | ... | ... | 1.30 (1.15-1.47)a |
Abbreviations: CACI, Charlson-Age Comorbidity Index; OR, odds ratio; RR, relative risk; ellipses, data not applicable.
a
Statistically significant (P < .05).
b
Metastasis indicates neck metastasis of N2 or higher or distant metastasis.