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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Nat Prod Rep. 2015 Jul;32(7):994–1006. doi: 10.1039/c5np00042d

Fig. 10.

Fig. 10

Model for the biosynthesis of the avoidance signal osas#9 in C. elegans. tbh-1 mutant worms produce large quantities of the shunt metabolite tsas#9 due to accumulation of the octopamine precursor tyramine.49