Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 30;10:138. doi: 10.3389/fncel.2016.00138

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Bosch, Muhaisen, Pujadas, Soriano and Martínez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Expression of Cofilin and p-Cofilin in Reelin-OE mice. (A) Left, immunoblot analysis of Cofilin in control, Reelin-OE, and DOX-treated Reelin-OE mice. Right, histogram showing densitometric analysis (n = 3 animals per group) by fold change in the three groups of mice (mean ± SEM; ANOVA test). (B) Left, immunoblot analysis of p-Cofilin in control, Reelin-OE, and DOX-treated Reelin-OE mice. Right, histogram showing densitometric analysis (n = 3 animals per group) by fold change in the three groups of mice (mean ± SEM; ANOVA test). (C–E) Examples of immunogold labeling against p-Cofilin in dendritic spines (s) receiving a synaptic contact from an axon terminal (at) in the SR of control (C), Reelin-OE (D), and DOX-treated Reelin-OE (E) mice. Note synaptic contacts indicated by arrowheads and immunolabeling dots by arrows. Scale bar, 250nm. (F) Histogram illustrating the proportion of dots in the synaptic contact, the extrasynaptic membrane and the intracellular domain of dendritic spines in the SR of Reelin-OE and DOX-treated Reelin-OE mice and their control littermates (mean ± SEM; *p < 0.05; ANOVA test).