Table 3. Univariate and multivariate Cox regression analysis of possible predictors of total mortality in the study population.
| Variables | Unadjusted HR (95% CI) | p | Adjusted HR (95% CI) | p |
| Age, 1-SD increase | 1.02 (0.99-1.05) | 0.06 | 1.04 (1.02-1.07) | 0.04 |
| Female gender | 2.38 (1.11-5.12) | 0.03 | 1.42 (0.49-4.18) | 0.52 |
| Smoking | 0.89 (0.37-2.16) | 0.81 | - | - |
| Systolic BP, 1-SD decrease | 1.02 (1.01-1.04) | 0.02 | 1.05 (1.001-1.11) | 0.04 |
| PESI score | 1.02 (1.02-1.03) | 0.01 | 1.02 (1.01-1.04) | 0.01 |
| RV diameter, 1-SD increase | 2.83 (1.39-5.76) | 0.01 | 2.27 (0.82-6.39) | 0.12 |
| McConnell’s sign | 1.28 (0.61-2.70) | 0.51 | - | - |
| sPAP | 1.06 (1.04-1.08) | 0.01 | 1.06 (1.030-1.09) | 0.01 |
| Thrombolytic treatment | 1.75 (0.84-3.67) | 0.14 | - | - |
| Troponin I, 1-SD increase | 1.56 (1.11-2.21) | 0.01 | 0.81 (0.41-1.58) | 0.52 |
| D-dimer, 1-SD increase | 1.001 (0.99-1.002) | 0.25 | - | - |
| BNP, 1-SD increase | 1.002 (1.001-1.003) | 0.01 | 1.001 (0.99-1.002) | 0.15 |
| Glucose, 1-SD increase | 1.22 (0.62-2.39) | 0.56 | - | - |
| Creatinine, 1-SD increase | 1.31 (0.57-3.01) | 0.53 | - | - |
| Hemoglobin, 1-SD decrease | 0.95 (0.88-1.03) | 0.24 | - | - |
| WBC, 1-SD increase | 1.0 (0.99-1.01) | 0.55 | - | - |
| RDW, 1-SD increase | 1.07 (0.92-1.25) | 0.37 | - | - |
| Platelets, 1-SD increase | 1.01 (0.99-1.02) | 0.41 | - | - |
| MPV, 1-SD increase | 1.01 (0.82-1.25) | 0.9 | - | - |
| NLR, 1-SD increase* | 1.16 (1.10-1.22) | 0.01 | 1.13 (1.04-1.23) | 0.01 |
| PLR, 1-SD increase* | 1.003 (1.001-1.005) | 0.01 | 1.002 (1.001-1.004) | 0.01 |
BNP, brain natriuretic peptide; BP, blood pressure; HR, hazard ratio; CI, confidence interval; MPV, mean platelet volume; NLR, neutrophil/lymphocyte ratio; PLR, platelet/lymphocyte ratio; RDW, red cell distribution width; RV, right ventricle; sPAP, systolic pulmonary arterial pressure; WBC, white blood cell count.
* NLR and PLR are entered into the model separately in order to prevent multicollinearity.