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. 2016 May 16;2016:2961954. doi: 10.1155/2016/2961954

Figure 1.

Figure 1

Dose-dependent effects of metformin on HG + H/R induced reduction in cell viability. H9C2 cells were treated with different concentrations of metformin (0, 1, 5, and 10 mM). A “+” symbol indicates presence and a “−” symbol indicates absence of the relevant treatment condition, such as HG (33 mM), H/R, and various concentrations of metformin. Cell viability of each group was estimated using the CCK-8 assay. Data are shown as means ± SD of 3 independent experiments. ∗ P < 0.05 versus Control; # P < 0.05 versus HG or H/R; & P < 0.05 versus metformin + HG + H/R.