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Pharmacokinetic parameter of drug determined after administered of plain drug and niosomal formulation.
| Sr. number | Parameters | Free drug | NC2 |
|---|---|---|---|
| 1 | C max | 2.488 μg/mL | 4.321 μg/mL |
| 2 | t max | 6 hr | 4 hr |
| 3 | AUC | 24.50 μg/mL·hr | 35.50 μg/mL·hr |
| 4 | AUMC | 160 μg/mL·hr2 | 670 μg/mL·hr2 |
| 5 | MRT | 6.66 hr | 18.87 hr |
