Table 1. The correlation between CtIP expression and clinicopathological variables.
Characteristics | No. of patients | Expression | Chi-square value | P value | |
---|---|---|---|---|---|
High | Low | ||||
Age/year | |||||
<55 | 75 | 62 | 13 | 0.45 | 0.5029 |
≥55 | 176 | 139 | 37 | ||
p53 status | |||||
Positive | 58 | 47 | 11 | 0.04 | 0.8355 |
Negative | 193 | 154 | 39 | ||
p53 mutation | |||||
Yes | 72 | 49 | 23 | 9.15 | 0.0025 |
No | 179 | 152 | 27 | ||
ER status | |||||
Positive | 213 | 174 | 39 | 2.27 | 0.1317 |
Negative | 34 | 24 | 10 | ||
PR status | |||||
Positive | 190 | 158 | 32 | 4.64 | 0.0312 |
Negative | 61 | 43 | 18 | ||
Histologic grade | |||||
1 | 67 | 58 | 9 | 4.94 | 0.0847 |
2 | 128 | 103 | 25 | ||
3 | 54 | 38 | 16 | ||
Tumor size, d/cm | |||||
≥2 | 139 | 103 | 36 | 6.98 | 0.0082 |
<2 | 112 | 98 | 14 | ||
Lymph nodes metastasis | |||||
Yes | 84 | 54 | 30 | 19.06 | <0.0001 |
No | 158 | 139 | 19 |
Data are presented as number.
ER: Estrogen receptor; PR:Progesterone receptor.
Features of breast cancer(χ2 text was used), using the public expression datasets GSE3494. CtIP expression is measured as log2 (probe intensities).