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. 2016 Jan 20;7(7):7829–7841. doi: 10.18632/oncotarget.6953

Table 4. The clinicopathological parameters of BC patients, n = 73.

Clinicopathological parameter N (%)
Age (year) ≤ 45 23 (31.5)
> 45 50 (68.5)
Menstrual status Premenopausal 39 (53.4)
Postmenopausal 34 (46.6)
Histological type Invasive ductal carcinoma 63 (86.3)
Invasive lobular carcinoma 3 (4.1)
Medullary carcinoma 2 (2.7)
Others 5 (6.8)
Tumor size T1 9 (12.3)
T2 57 (78.1)
T3 3 (4.1)
T4 4 (5.5)
Lymph node status N0 30 (41.1)
N1 33 (45.2)
N2 4 (5.5)
N3 6 (8.2)
Estrogen receptor Positive 36 (49.3)
Negative 33 (45.2)
No data 4 (5.5)
Progesterone receptor Positive 38 (52.1)
Negative 31 (42.5)
No data 4 (5.5)
HER2 0/+ 51 (69.9)
++ 11 (15.1)
+++ 6 (8.2)
No data 5 (6.8)
Molecular subtype Luminal B 45 (61.6)
Triple-negative 18 (24.7)
HER2-positive 10 (13.7)
Histological form Unicentric 50 (68.5)
Multicentric 23 (31.5)
Pathomorphosis 1 rate 21 (28.8)
2 rate 23 (31.5)
3 rate 6 (8.2)
4 rate 4 (5.5)
No data 19 (26.0)
Grade 1 rate 2 (2.7)
2 rate 53 (72.6)
3 rate 6 (8.2)
No data 12 (16.4)
NAC regimen CAX 23 (31.5)
FAC 36 (49.3)
Taxotere 14 (19.2)
NAC response Complete response 5 (6.8)
Partial response 40 (54.8)
Stable disease 20 (27.4)
Progressive disease 8 (11.0)

Abbreviations: NAC, neoadjuvant chemotherapy; CAX, Cyclophosphamide-Adriamycin-Xeloda; FAC, 5-Fluorourail-Adriamycin-Cyclophosphamide; HER2 testing is performed in accordance with American Society of Clinical Oncology/College of American Pathologists Guideline 2007 Recommendation [41].