Table 4. The clinicopathological parameters of BC patients, n = 73.
Clinicopathological parameter | N (%) | |
---|---|---|
Age (year) | ≤ 45 | 23 (31.5) |
> 45 | 50 (68.5) | |
Menstrual status | Premenopausal | 39 (53.4) |
Postmenopausal | 34 (46.6) | |
Histological type | Invasive ductal carcinoma | 63 (86.3) |
Invasive lobular carcinoma | 3 (4.1) | |
Medullary carcinoma | 2 (2.7) | |
Others | 5 (6.8) | |
Tumor size | T1 | 9 (12.3) |
T2 | 57 (78.1) | |
T3 | 3 (4.1) | |
T4 | 4 (5.5) | |
Lymph node status | N0 | 30 (41.1) |
N1 | 33 (45.2) | |
N2 | 4 (5.5) | |
N3 | 6 (8.2) | |
Estrogen receptor | Positive | 36 (49.3) |
Negative | 33 (45.2) | |
No data | 4 (5.5) | |
Progesterone receptor | Positive | 38 (52.1) |
Negative | 31 (42.5) | |
No data | 4 (5.5) | |
HER2 | 0/+ | 51 (69.9) |
++ | 11 (15.1) | |
+++ | 6 (8.2) | |
No data | 5 (6.8) | |
Molecular subtype | Luminal B | 45 (61.6) |
Triple-negative | 18 (24.7) | |
HER2-positive | 10 (13.7) | |
Histological form | Unicentric | 50 (68.5) |
Multicentric | 23 (31.5) | |
Pathomorphosis | 1 rate | 21 (28.8) |
2 rate | 23 (31.5) | |
3 rate | 6 (8.2) | |
4 rate | 4 (5.5) | |
No data | 19 (26.0) | |
Grade | 1 rate | 2 (2.7) |
2 rate | 53 (72.6) | |
3 rate | 6 (8.2) | |
No data | 12 (16.4) | |
NAC regimen | CAX | 23 (31.5) |
FAC | 36 (49.3) | |
Taxotere | 14 (19.2) | |
NAC response | Complete response | 5 (6.8) |
Partial response | 40 (54.8) | |
Stable disease | 20 (27.4) | |
Progressive disease | 8 (11.0) |
Abbreviations: NAC, neoadjuvant chemotherapy; CAX, Cyclophosphamide-Adriamycin-Xeloda; FAC, 5-Fluorourail-Adriamycin-Cyclophosphamide; HER2 testing is performed in accordance with American Society of Clinical Oncology/College of American Pathologists Guideline 2007 Recommendation [41].