Table 3. Multivariate cox regression analyses of patients with stage IIIC epithelial ovarian cancer with node-positive.
Characteristic | CSS | OS | ||||
---|---|---|---|---|---|---|
HR | 95%CI | P | HR | 95%CI | P | |
Age (years) | ||||||
≤50 | 1 | 1 | ||||
> 50 | 1.331 | 1.709-2.104 | < 0.001 | 1.425 | 1.301-1.560 | < 0.001 |
Grade | ||||||
Well | 1 | 1 | ||||
Moderately | 2.049 | 1.619-2.595 | < 0.001 | 1.933 | 1.552-2.407 | < 0.001 |
Poorerly | 2.258 | 1.806-2.823 | < 0.001 | 2.103 | 1.709-2.588 | < 0.001 |
Undifferentiated | 2.325 | 1.836-2.944 | < 0.001 | 2.150 | 1.725-2.679 | < 0.001 |
Histology | ||||||
Serous | 1 | 1 | ||||
Mucinous | 1.264 | 1.001-1.597 | 0.049 | 1.334 | 1.074-1.656 | 0.009 |
Endometroid | 0.879 | 0.766-1.009 | 0.068 | 0.910 | 0.799-1.036 | 0.153 |
Clear cell | 1.370 | 1.121-1.676 | 0.002 | 1.424 | 1.183-1.716 | < 0.001 |
Undifferentiated | 0.698 | 0.463-1.053 | 0.087 | 0.713 | 0.484-1.051 | 0.088 |
Tumor location | ||||||
One site | 1 | 1 | ||||
Paired site | 1.722 | 1.298-2.284 | < 0.001 | 1.612 | 1.225-2.121 | 0.001 |
Bilateral site | 1.257 | 1.159-1.364 | < 0.001 | 1.199 | 1.110-1.296 | < 0.001 |
Number of RLNs (continuous variable) | 0.998 | 0.993-1.003 | 0.339 | 0.996 | 0.991-1.001 | 0.081 |
Number of PLNs (continuous variable) | 1.007 | 0.998-1.016 | 0.144 | 1.008 | 0.999-1.017 | 0.070 |
LNR (continuous variable) | 1.896 | 1.709-2.104 | < 0.001 | 1.679 | 1.454-1.939 | < 0.001 |