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. 2016 Jan 12;7(7):7979–7992. doi: 10.18632/oncotarget.6888

Figure 1. SSA shows greater potency to inhibit breast cancer cell growth compared to SS.

Figure 1

a. The chemical structure schemes of SS and SSA. b. Breast cancer MCF-7, MDA-MB-231, BT-20, and SKBR-3 cells were treated with SS at 25, 50, 75, 100, 125, 150, and 175 μM for 36 h. c. Breast cancer MCF-7, MDA-MB-231, BT-20, and SKBR-3 cells were treated with SSA at 1, 2, 4, 8, 16, 32, and 64 μM for 36 h. Cell growth inhibitory activity was evaluated by using Cell Titer-Glo Assay, which measures viable cell numbers based on ATP content. The relative cell viability was computed and the growth inhibition curve was plotted in which IC50 was calculated by using GraphPad Prism 6.