Table 2. Cytoplasmic AQP1 expression in IDC patients.
| Pathological features | Cases | AQP1 score, n (%) | rs | P | ||
|---|---|---|---|---|---|---|
| 0 | 1–2 | 3–9 | ||||
| Age, y | 0.082 | 0.139 | ||||
| < 50 | 146 | 41 (28.1) | 56 (38.3) | 49 (33.6) | ||
| ≥ 50 | 178 | 35 (19.7) | 75 (42.1) | 68 (38.2) | ||
| Histological gradea | 0.186 | 0.001 | ||||
| I | 34 | 14 (41.2) | 12 (35.3) | 8 (23.5) | ||
| II | 234 | 56 (23.9) | 98 (41.9) | 80 (34.2) | ||
| III | 53 | 6 (11.3) | 21 (39.6) | 26 (49.1) | ||
| Tumor size, cm | 0.130 | 0.020 | ||||
| ≤ 2 | 90 | 30 (33.3) | 37 (41.1) | 23 (25.6) | ||
| 2–5 | 214 | 40 (18.7) | 86 (40.2) | 88 (41.1) | ||
| > 5 | 20 | 6 (30.0) | 8 (40.0) | 6 (30.0) | ||
| Lymph node metastasis | 0.129 | 0.020 | ||||
| Negative | 145 | 38 (26.2) | 66 (45.5) | 41 (28.3) | ||
| Positive | 179 | 38 (21.2) | 65 (36.3) | 76 (42.5) | ||
| pTNM | 0.202 | 0.000 | ||||
| I | 55 | 20 (36.4) | 23 (41.8) | 12 (21.8) | ||
| II | 185 | 43 (23.2) | 78 (42.2) | 64 (34.6) | ||
| III–IV | 84 | 13 (15.5) | 30 (35.7) | 41 (48.8) | ||
| Recurrence or distant metastasis | 0.138 | 0.013 | ||||
| NO | 270 | 66 (24.4) | 116 (43.0) | 88 (32.6) | ||
| Yes | 54 | 10 (18.5) | 15 (27.8) | 29 (53.7) | ||
| ER statusa | −0.120 | 0.031 | ||||
| Negative | 92 | 14 (15.2) | 39 (42.4) | 39 (42.4) | ||
| Positive | 231 | 62 (26.8) | 92 (39.8) | 77 (33.3) | ||
| PR statusa | −0.159 | 0.004 | ||||
| Negative | 68 | 11 (16.2) | 22 (32.3) | 35 (51.5) | ||
| Positive | 255 | 65 (25.5) | 109 (42.7) | 81 (31.8) | ||
| Her2 statusa | 0.075 | 0.178 | ||||
| – ∼ + | 252 | 60 (23.8) | 108 (42.9) | 84 (33.3) | ||
| ++ ∼ +++ | 71 | 16 (22.5) | 23 (32.4) | 32 (45.1) | ||
a
Some missing data