Table 4. Univariate and multivariate Cox regression analyses of predictors of overall survival.

Variable	R	Cl (95%)	P
Univariate analysis (n = 233)
Age	2.200	1.325–3.652	0.002
Gender	0.641	0.351–1.172	0.149
T stage (T1–2/T3–4)	2.300	1.355–3.903	0.002
N stage (N0/N1–3)	2.414	1.267–4.601	0.007
Clinical stage (I–II/III–IV)	2.958	1.512–5.786	0.002
Lox (low/high)	1.825	1.138–2.927	0.013
WHO histological classification	1.075	0.643–1.797	0.784
Multivariate analysis (n = 233)
Age	2.115	1.271–3.519	0.004
Clinical stage (I–II/III–IV)	1.783	1.108–2.868	0.017
Lox (low/high)	3.159	1.612–6.191	0.001

HR, hazard ratio; 95% CI, 95% confidence interval; LOX, lysyl oxidase.