Skip to main content
. 2016 Jan 27;7(7):8310–8320. doi: 10.18632/oncotarget.7027

Figure 1. Mutation of predisposing genes in breast cancer patients with early-onset or a family history.

Figure 1

(A) Each of the predisposing genes identified in the patients is listed on the left. A family history is shown in black. For the molecular types, HR(+)Her2(−) breast cancer is colored pink, HR(+)Her2(+) orange, HR(−)Her2(+) light green, and TNBC purple. (B) Twenty-five mutations of a predisposing gene were identified, 1 (4.0%) in ATM, 8 (32.0%) in BRCA1, 10 (40.0%) in BRCA2, and 1 each (4.0%) in BRIP1, FANCI, MSH2, RAD50, RAD51C, and TP53.