Table 1.
H. pylori vacA genotypes and cagA status in patients from Macau, China.
Chronic Gastritis (n = 234) | Gastric Carcinoma (n = 47) | p-Value | Total | |
---|---|---|---|---|
vacA i-region 1 | ||||
i1 | 172 (85.1%) | 29 (85.3%) | >0.999 | 201 (85.2%) |
i2 | 30 (14.9%) | 5 (14.7%) | 35 (14.8%) | |
vacA m-region 2 | ||||
m1 | 94 (53.7%) | 17 (47.2%) | 0.583 | 111 (52.6%) |
m2 | 81 (46.3%) | 19 (52.8%) | 100 (47.4%) | |
vacA s-region 3 | ||||
s1 | 189 (91.7%) | 38 (88.4%) | 0.553 | 227 (91.2%) |
s2 | 17 (8.3%) | 5 (11.6%) | 22 (8.8%) | |
cagA status | ||||
positive | 208 (88.9%) | 38 (80.9%) | 0.146 | 246 (87.5%) |
negative | 26 (11.1%) | 9 (19.1%) | 35 (12.5%) |
1 Nine cases (three gastritis and six carcinomas) could not be genotyped and multiple strains were detected in 36 cases (29 gastritis and seven carcinomas); 2 One carcinoma case could not be genotyped and multiple strains were detected in 69 cases (59 gastritis and 10 carcinomas); 3 Five cases of gastritis could not be genotyped and multiple strains were detected in 27 cases (23 gastritis and four carcinomas).