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. 2016 May 17;8(5):155. doi: 10.3390/toxins8050155

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© 2016 by the author; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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ADAM_CR domain. Ribbon representation of the C_h subdomains of catrocollastatin/VAP2B (A) and the D* domain of ADAMTS5 (B). (C) Topology diagram of the ADAM_CR domain. Gallery of the group-A (C) and group-B (D) ADAM_CR domain structures. Conserved α-helix and β-strands are shown in red and yellow, respectively. Disulfide bonds, residues in HVR, and the residues in the V-loop are shown in orange, blue, and gray, respectively. The PDB ID for each protein structure is indicated in parentheses.