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Immunohistochemical analysis of phospho-SRCY416 in human tumor xenografts. (a) Images of representative sections (low and high resolution) of HCT116 xenografts from (left) untreated mice and (right) mice treated with 11a (n = 4). (b) Histoscore analysis (6–7 sections analyzed per experiment). Quantification of immunohistochemistry across tumor tissue sections from untreated animals (water) and 11a treated groups performed in blinded fashion. P value calculated from t-test.
