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. 2016 Feb 25;59(10):4462–4475. doi: 10.1021/acs.jmedchem.5b01865

Figure 3.

Figure 3

ITC analysis of compounds 1 and 2 (T = 293.15 K). (a) Compound 1 binds with a KD value of 15.4 nM (ΔH = −12.1 kcal/mol) and (b) 2 binds with a KD value of 14.1 nM (ΔH = −11.2 kcal/mol).