Table 3.
Frequency of cmTreg cells during the first year after liver transplantation
Biomarker | % CD4+CD25highghCD45RO+CD62L+ | % CD4+CD25highghCD45RO+CD62L+ | ||||
---|---|---|---|---|---|---|
Profile | NAR (n = 44) | AR (n = 15) | P value | NHCVR (n = 46) | HCVR (n = 16) | P value |
Basal | 3.19±1.79 | 3.91±1.94 | 0.144 | 3.60±1.94 | 2.61±1.21 | 0.100 |
First week | 5.71±4.09 | 8.47±5.82 | 0.145 | 6.84±4.63 | 5.00±5.75 | 0.162 |
Second week | 4.88±3.15 | 5.95±4.04 | 0.475 | 5.34±3.19 | 4.43±4.58 | 0.245 |
First month | 2.84±2.29 | 4.53±2.71 | 0.028* | 3.74±2.49 | 1.91±2.01 | 0.005** |
Second month | 1.80±0.93 | 2.66±1.85 | 0.376 | 2.18±1.13 | 1.77±1.47 | 0.141 |
Third month | 2.12±1.54 | 4.09±2.87 | 0.166 | 2.90±2.21 | 1.66±1.29 | 0.176 |
Sixth month | 2.36±1.72 | 2.90±1.78 | 0.433 | 3.03±1.80 | 1.40±0.82 | 0.002** |
First year | 2.59±1.76 | 1.49±0.50 | 0.201 | 2.86±1.80 | 1.34±0.22 | 0.038* |
The frequency of cmTreg cells from patients with AR (n = 15) and NAR (n = 49) were monitored during the first year after OLT and are represented as mean ± SD. The frequency of cmTreg cells from patients who had suffered HCVR (n = 16) or NHCVR (n = 48) are represented as mean ± SD.
*P < 0.05; **P < 0.01.