Table 2.
Agreement of flare status between patient, MD and DAS28 worsening criteria by disease activity level
| Patient |
Agreement |
|||||
|---|---|---|---|---|---|---|
| Flare classification (Visit 2) | Flare status | Yes | No | Observed | Expected (%) | AC1 κ |
| MD flare classification (n=718) | ||||||
| All | Yes | 98 (58%) | 135 (25%) | 512 (71%) | 59 | 0.52 |
| No | 71 (42%) | 414 (75%) | ||||
| Remission | Yes | 5 (23%) | 39 (16%) | 212 (79%) | 78 | 0.73 |
| No | 17 (77%) | 207 (84%) | ||||
| Low disease activity | Yes | 8 (50%) | 17 (29%) | 49 (66%) | 59 | 0.44 |
| No | 8 (50%) | 41 (71%) | ||||
| Moderate disease activity | Yes | 37 (69%) | 40 (45%) | 86 (60%) | 49 | 0.21 |
| No | 17 (31%) | 49 (55%) | ||||
| High disease activity | Yes | 23 (79%) | 11 (65%) | 29 (63%) | 56 | 0.35 |
| No | 6 (21%) | 6 (35%) | ||||
| DAS28 criterion flare classification (n=515) | ||||||
| All | ≥1.2/0.6 | 36 (31%) | 48 (12%) | 388 (75%) | 69 | 0.64 |
| <1.2/0.6 | 79 (69%) | 352 (88%) | ||||
| Remission | ≥1.2/0.6 | 0 (0%) | 1 (0%) | 232 (89%) | 89 | 0.88 |
| <1.2/0.6 | 27 (100%) | 232 (100%) | ||||
| Low disease activity | ≥1.2/0.6 | 2 (13%) | 7 (12%) | 54 (73%) | 72 | 0.63 |
| <1.2/0.6 | 13 (87%) | 52 (88%) | ||||
| Moderate disease activity | ≥1.2/0.6 | 21 (40%) | 33 (36%) | 80 (56%) | 53 | 0.17 |
| <1.2/0.6 | 31 (60%) | 59 (64%) | ||||
| High disease activity | ≥1.2/0.6 | 13 (62%) | 7 (44%) | 22 (59%) | 51 | 0.20 |
| <1.2/0.6 | 8 (38%) | 9 (56%) | ||||
AC, agreement coefficient; DAS, Disease Activity Score.