Fig. 3.

Effects 2-BFI alone or in combination with different proportions of fentanyl (top row), buprenorphine (middle row), or NAQ (bottom row) on CFA-induced mechanical nociception (n = 6/group) (left column), CFA-induced thermal nociception (n = 6/group) (middle column), and schedule-controlled responding (n = 8) (right column). Ordinates: percentage of maximum possible effects (left and middle columns) or percentage of control responding rate (right column); abscissa: dose of 2-BFI in the mixture (mg/kg, i.p.). Error bars are not shown for all combination studies for clarity.