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. 2016 Jun;357(3):509–519. doi: 10.1124/jpet.116.232421

TABLE 2.

ED50 values (95% CL) for fentanyl alone and in combination with NAQ in the assay of mechanical nociception and the dose ratios between them

Treatment ED50 (95% CL) Dose Ratio
Fentanyl alone 0.018 (0.012, 0.027)
0.32 NAQ/fent 0.032 (0.021, 0.049) 1.80
Fentanyl alone 0.021 (0.012, 0.035)
1 NAQ/fent 0.061 (0.039, 0.098) 2.90
Fentanyl alone 0.016 (0.009, 0.030)
3.2 NAQ/fent 0.137 (0.087, 0.216) 8.50
Fentanyl alone 0.028 (0.023, 0.036)
5.6 NAQ/fent 0.459 (0.327, 0.644) 16.12

fent, fentanyl.