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In chemico effects of selected cytoprotectants on NAPQI-induced (A) or acrolein-induced (B) loss of GSH sulfhydryl groups. Graded concentrations of toxicant were incubated with selected test hepatoprotective compounds. Data are expressed as mean percent control ± S.E.M. (n = 3 to 4 experiments) and calculated IC50 values are provided in parentheses. 2-ACP, 2-acetylcyclopentanone; Phl, phloretin.
