Fig. 8.

Effects of graded cytoprotectant concentrations (0.25–5.0 mM) on temporal loss of viability induced by APAP exposure (1.0 mM). After 2 hours of APAP incubation, cytoprotectant was added and viability was determined after additional 2 hours. Note: Fig. 8C only pertains to the representative effects of 2-ACP and NAC. Data are expressed as mean percent of control ± S.E.M. (n = 6–8) cell viability. *P < 0.05 (level of significance relative to the APAP alone control data after 4 hours of incubation).