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. 2016 Mar 23;62(12):1564–1568. doi: 10.1093/cid/ciw151

Table 1.

Estimated Clinical Outcomes by Cryptococcal Meningitis Induction Treatment Regimen

Induction Regimen 2-Week Survival Probability (95% CI) 10-Week Survival Probability (95% CI) 26-Week Survival Probability (95% CI)
Amphotericin B 0.75 (.67–.84) 0.56 (.47–.66) 0.46 (.37–.57)
US estimate 0.875 (.835–.920) 0.812 (.768–.860) 0.778 (.735–.830)
Amphotericin B + 5FC 0.85 (.78–.92) 0.69 (.61–.79) 0.65 (.56–.75)
US estimate 0.925 (.890–.960) 0.872 (.833–.917) 0.858 (.817–.903)
Amphotericin B + fluconazole 0.80 (.73–.88) 0.67 (.58–.77) 0.55 (.45–.65)
US estimate 0.90 (.865–.940) 0.857 (.815–.903) 0.817 (.772–.863)

Source: Day et al [8].

Abbreviations: 5FC, flucytosine; CI, confidence interval.