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Multivariate model: association between clinical characteristics, iCOGS single nucleotide polymorphisms, and upgrading in the surgical cohort
| SNP | OR | 95% CI | p value |
|---|---|---|---|
| Age | 1.03 | 1.02–1.05 | 0.007 |
| PSA | 1.05 | 1.01–1.10 | 0.04 |
| rs11568818 | 1.46 | 1.17–1.82 | 0.0009 |
| rs2427345 | 1.32 | 1.05–1.65 | 0.02 |
| rs7141529 | 1.14 | 0.92–1.42 | 0.25 |
CI = confidence interval; OR = odds ratio; PSA = prostate-specific antigen; SNP = single nucleotide polymorphism.
