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. Author manuscript; available in PMC: 2017 Jun 14.
Published in final edited form as: J Biomech. 2016 Apr 2;49(9):1649–1657. doi: 10.1016/j.jbiomech.2016.03.053

Table 5.

Multiple mediator modeling with a single independent variable

Dependent Variable Independent Variable Re-Alignment Crimp Deformation Sliding
S RA TR LR F A 1% 3% 5% 7% 1% 3% 5% 7%
PYD M M M* M*
Linear Modulus PYD M M* M M*
Dynamic Modulus PYD M M* M* M M M M*
Tangent Delta PYD M M*
Max Stress PYD M* M M*
Stress Relaxation PYD M*
Tangent Stiffness PYD M M M* M* M M*
Hysteresis PYD M* M* M*
MIDSUBSTANCE Toe Modulus FibDiam M* M* M*
Linear Modulus FibDiam M M M* M M M*
Dynamic Modulus FIbDens M M* M* M
Tangent Delta FibDiam M M* M* M
Max Stress FibDiam M* M M M M M* M* M
Stress Relaxation FibDiam M* M M* M* M
Tangent Stiffness FibDiam M M* M* M*
Hysteresis FibDiam M M* M*

Note: PYD = pyridinoline content, FibDiam = fibril diameter; S = ReAlignStrain, RA = ReAlignAmount, TR = ToeReAlign, LR = LinearReAlign, F = CrimpFreq, A = CrimpAmp; P = predictor, M = mediator+predictor, M* = mediator+strong predictor (top 3 predictive properties)