Expression of APN receptors in retinal neuronal layers and blood vessels in normal and hypoxic retinas at P17, when maximal neovascularization is observed in the mouse model of oxygen-induced retinopathy. Schematic of the laser-capture microdissected retinal layers (DAPI for nuclei, blue) and blood vessels (lectin, red) is shown (outlined with dotted line). Expression of adipoR1, adipoR2, and T-cadherin was examined by using qPCR. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer.
Adapted from Fu et al, AJCN, 2015, 101 (4): 879–88