Appendix Table 2.
Baseline estimates (mean (standard error (SE))(a) and change from baseline in quantitative sensory testing (QST) measures according to sleep quality for incident TMD cases and match controls in the OPPERA nested case-control study (n=431)
| Baseline sleep quality | P | ||||
|---|---|---|---|---|---|
| Good (PSQI 0-3) | Moderate (PSQI >3-5) | Poor (PSQI >5) | |||
| Baseline QST measures | Mean (SE) | Mean (SE) | Mean (SE) | ||
| Trapezius pressure pain threshold (kPa) | Case | 316 (17) | 370 (17) | 349 (13) | 0.3(d) |
| Matched control | 356 (15) | 370 (18) | 337 (20) | ||
| P=0.5(b) | P=0.1(c) | ||||
| Mean pinprick pain rating (0-100) (N=378) | Case | 18.0 (2.6) | 14.4 (2.7) | 17.8 (2.0) | 0.9(d) |
| Matched control | 22.4 (2.3) | 16.7 (2.7) | 20.8 (3.3) | ||
| P=0.1(b) | P=0.2(c) | ||||
| Pinprick post-stimulus rating (0-100) (N=377) | Case | 2.35 (1.0) | 2.71 (1.1) | 2.91 (0.8) | 0.4(d) |
| Matched control | 3.78 (1.0) | 1.97 (1.1) | 5.11 (1.3) | ||
| P=0.3(b) | P=0.3(c) | ||||
| Change from baseline QST measures | |||||
| Delta: trapezius pressure pain threshold (kPa) | Case | −41.4 (17) | −81.0 (17) | −49.9 (13) | 0.1(d) |
| Matched control | 13.1 (15) | 35.6 (18) | 60.2 (21) | ||
| P<0.0001(b) | P=0.3(c) | ||||
| Delta: Mean pinprick pain rating (0-100) (N=362) | Case | 6.60 (2.9) | 6.23 (3.0) | 3.05 (2.2) | 0.6(d) |
| Matched control | −1.98 (2.6) | −1.47 (2.9) | −0.06 (3.6) | ||
| P=0.005(b) | P=0.9(c) | ||||
| Delta: Pinprick post-stimulus rating (0-100) (N=362) | Case | 4.34 (1.2) | 1.24 (1.3) | 1.45 (0.9) | 0.3(d) |
| Matched control | −0.32 (1.1) | 0.14 (1.3) | −1.59 (1.5) | ||
| P=0.003(b) | P=0.2(c) | ||||
All mean estimates are adjusted for study site
P-value testing the null hypothesis of no statistically significant difference in baseline mean sleep quality between incident cases and matched controls (i.e. main effect)
P-value for testing the null hypothesis of no statistical significant difference between good, moderate and poor sleep quality (i.e. main effect)
P-value from the likelihood ratio test that assesses the statistical significance of the effect modification of the QST measures on the relationship between sleep quality and TMD case status (i.e. interaction)