. 2016 May 31;10:242. doi: 10.3389/fnins.2016.00242

Table 1.

Statistical analysis of the behavioral data.

Behavioral Test	N	Measurement	Statistical test		Factor	Statistic	p-value	Figures
Novelty suppressed feeding	15–18 mice/group	Hazard ratio	Cox proportional hazards model		Induction	$χ_{(1)}^{2}$ = 1.4807	0.2237	Figure 2
					Treatment	$χ_{(1)}^{2}$ = 21.7498	<0.0001
					Interaction	$χ_{(1)}^{2}$ = 5.3018	0.0213
			Subgroup treatment effects	CTRL mice	Treatment	$χ_{(1)}^{2}$ = 21.7498	<0.0001	Figure 2A
				iGluN2B^Nes mice	Treatment	$χ_{(1)}^{2}$ = 5.1273	0.0236	Figure 2A
		Homecage consumption	2-way ANOVA		Induction	F_{(1, 61)} = 0.375	0.5424	Figure 2B
					Treatment	F_{(1, 61)} = 1.305	0.2578
					Interaction	F_{(1, 61)} = 0.115	0.7357
		% Weight change	2-way ANOVA		Induction	F_{(1, 61)} = 0.196	0.6596	Figure 2B
					Treatment	F_{(1, 61)} = 0.014	0.9047
					Interaction	F_{(1, 61)} = 0.023	0.8811
Elevated plus maze	15–18 mice/group	Open arm time	2-way ANOVA		Induction	F_{(1, 61)} = 0.098	0.7555	Figure 3A
					Treatment	F_{(1, 61)} = 0.643	0.4258
					Interaction	F_{(1, 61)} = 0.031	0.8610
		Open arm entries	2-way ANOVA		Induction	F_{(1, 61)} = 0.966	0.3295	Figure 3B
					Treatment	F_{(1, 61)} = 0.575	0.4511
					Interaction	F_{(1, 61)} = 0.082	0.7756
		Open arm distance	2-way ANOVA		Induction	F_{(1, 61)} = 0.358	0.5518	Figure 3C
					Treatment	F_{(1, 61)} = 0.214	0.6457
					Interaction	F_{(1, 61)} < 0.0001	0.9989
		Total Distance	2-way ANOVA		Induction	F_{(1, 61)} = 0.437	0.5112	Figure 3D
					Treatment	F_{(1, 61)} = 2.947	0.0911
					Interaction	F_{(1, 61)} = 0.605	0.4398
Tail Suspension Test	15–18 mice/group	Immobility	2-way repeated measures ANOVA		Induction	F_{(1, 60)} = 0.346	0.5585	Figure 3E
					Treatment	F_{(1, 60)} = 1.982	0.1644
					Interaction	F_{(1, 60)} = 0.001	0.9706
					Minute	F_{(4, 240)} = 114.851	<0.0001
					Minute × induction	F_{(4, 240)} = 0.386	0.8187
					Minute × treatment	F_{(4, 240)} = 4.136	0.0029
					Minute × induction × treatment	F_{(4, 240)} = 0.124	0.9737
		Immobility (last 2 min)	2-way ANOVA		Induction	F_{(1, 60)} = 0.023	0.8809	Figure 3F
					Treatment	F_{(1, 60)} = 10.402	0.0020
					Interaction	F_{(1, 60)} = 0.027	0.8692
			Planned Comparison t-test	CTRL mice	Treatment	t₍₂₉₎ = 2.389	0.0236
				iGluN2B^Nes mice	Treatment	t₍₃₁₎ = 2.174	0.0375

p < 0.05 are highlighted in bold.