Table 3. Comparison between exacerbator and non-exacerbator for previous 12 months at initial visit.
| Parameters | Exacerbator (n=212) | Non-exacerbator (n=596) | Odds ratio | 95% CI | P |
|---|---|---|---|---|---|
| Age (y) | 72.0±7.4 | 71.4±7.9 | 0.37 | ||
| Male, n (%) | 197 (92.9) | 549 (92.6) | 1.05 | 0.57–1.93 | 0.87 |
| Chronic bronchitis, n (%) | 92 (43.4) | 190 (31.9) | 1.63 | 1.19–2.26 | <0.01 |
| Post-BD FEV1 (%) | 52.1±17.7 | 59.2±15.6 | <0.001 | ||
| DLCO (%) | 70.1±25.0 | 77.1±23.5 | <0.001 | ||
| CB_DLCO, n (%) | <0.001 | ||||
| CB (+) low DLCO | 38 (17.9) | 44 (7.4) | |||
| CB (+) high DLCO | 54 (25.5) | 146 (24.5) | |||
| CB (−) low DLCO | 33 (15.6) | 81 (13.6) | |||
| CB (−) high DLCO | 87 (41.0) | 325 (54.5) | |||
| CAT | 16.9±8.3 | 14.5±7.2 | <0.001 | ||
| Current smoker, n (%) | 44 (23.9) | 181 (34.0) | 0.61 | 0.41–0.90 | 0.01 |
Post-BD FEV1, post bronchodilator forced expiratory volume for 1 second; DLCO, diffusing capacity of the lung for carbon monoxide; CB_DLCO, the parameter which was generated by combination of chronic bronchitis symptom and level of DLCO; CB (+) low DLCO, patients with chronic bronchitis and DLCO <60% of predictive value; CB (+) high DLCO, patients with chronic bronchitis and DLCO ≥60% of predictive value; CB (−) low DLCO, patients without chronic bronchitis and DLCO <60% of predictive value; CB (−) high DLCO, patients without chronic bronchitis and DLCO ≥60% of predictive value; mMRC, modified Medical Research Council Dyspnea scale; CAT, COPD assessment test.