Table 2. Cases of Mycoplasma pneumoniae (Mp) infections associated with PMI in the literature.
Source | Age (yr) | Clinical features | Imaging manifestations | Histopathological findings | Outcome |
---|---|---|---|---|---|
Foy et al., 1971 | 40 | Fever (38 °C), nonproductive cough, muscle ache; WBC: 11.3 g/L (82% neutrophils); throat culture positive for Mp; CF antilipid antibody titer for Mp: 1:8 |
Incomplete consolidation of left lower lobe changed into infiltrate in right perihilar region 4 and a half years later | NP | Erythromycin (500 mg twice daily); symptoms resolved |
Miyagawa et al., 1991 | 71 | Fever, malase; ESR: 120 mm/h; anti-mycoplasma antibody titer raised (not in detail) |
PMI (not in detail) | Polypoid granulation tissue with nuclear debris in the lumen of respiratory bronchiole, re-epithelialization on surface of organization tissue | Minocycline; symptoms resolved |
Llibre et al., 1997 | 57 | Fever (37.7 °C), cough, exertional dyspnea; WBC: 13.9 g/L (72% neutrophils); ESR: 100 mm/h; anti-mycoplasma IgG antibody first titer 1.05 and second titer 2.95 (4 weeks later) |
Bilateral, mainly peripheral, migratory patchy infiltrates in the lower right lobe and left upper lobe | Fibroblastic tissue within bronchioles, alveolar ducts, and peribronchiolar alveolar spaces, interstitial infiltrate of mononuclear inflammatory cells | Oral prednisone; symptoms resolved |
Yang et al., 2008 | 11 | Fever (38.3 °C), shortness of breath, sore throat; WBC: 12.2 g/L (8.3% eosinophils); serum IgE: 770 IU/mL; PCR detection positive for Mp |
Four pulmonary masses in bilateral lower lobes and left upper lobe changed into interval development of diffuse tiny centrilobular nodules and mild hilar lymphadenopathy | NP | Azithromycin and budesonide nebulizer; symptoms resolved |
WBC, white blood cells; Mp, Mycoplasma pneumoniae; CF, complement-fixation; NP, not performed; ESR, erythrocyte sedimentation rate; PMI, pulmonary migratory infiltrates.