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The heterogeneous strong granular cytoplasmic staining in some tumor cells of different primary tumor areas by IHC. (A) Heterogeneous granular cytoplasmic staining pattern throughout the section (40×); (B) strong granular cytoplasmic staining in most tumor cells (red square area’s magnification in Figure 3A, 200×); (C) most tumor cells without strong granular cytoplasmic staining pattern (green square area’s magnification in Figure 3A, 200×). IHC, immunohistochemistry.
