Table 3.
Comparisons of clinical parameters before and after treatment in patients with MCNS based on the remission criterion of UPE <300 mg/g creatinine
| Parameter | Remission |
Nonremission |
||||
|---|---|---|---|---|---|---|
| before treatment | after treatment | p | before treatment | after treatment | p | |
| Number of subjects | 13 | 13 | 10 | 10 | ||
| Age, years | 43 ± 18 | 44 ± 18 | 42 ± 19 | 43 ± 19 | ||
| Men/women | 6/7 | 6/7 | 6/4 | 6/4 | ||
| Waking systolic BP, mm Hg | 132 ± 12 | 138 ± 17 | 0.173 | 136 ± 13 | 132 ± 15 | 0.575 |
| Waking diastolic BP, mm Hg | 78 ± 8 | 80 ± 7 | 0.152 | 85 ± 12 | 82 ± 13 | 0.241 |
| Sleeping systolic BP, mm Hg | 125 ± 10 | 122 ± 8 | 0.975 | 132 ± 16 | 125 ± 17 | 0.203 |
| Sleeping diastolic BP, mm Hg | 73 ± 9 | 69 ± 8 | 0.753 | 82 ± 12 | 76 ± 13 | 0.169 |
| Sleeping/waking systolic BP ratio, % | 95 ± 6 | 89 ± 9 | 0.044 | 97 ± 4 | 95 ± 5 | 0.721 |
| Sleeping/waking diastolic BP ratio, % | 94 ± 6 | 87 ± 10 | 0.133 | 96 ± 6 | 93 ± 7 | 0.386 |
| SAC, g/dl | 1.7 ± 0.5 | 3.8 ± 0.8 | 0.002 | 1.8 ± 0.7 | 3.0 ± 0.9 | 0.013 |
| eGFR, ml/min/1.73 m2 | 78 ± 18 | 75 ± 15 | 0.530 | 72 ± 17 | 76 ± 24 | 0.721 |
| Log urinary protein-to-creatinine ratio, mg/g creatinine | 3.7 ± 0.5 | 1.7 ± 0.3 | <0.001 | 3.8 ± 0.3 | 3.5 ± 0.5 | 0.051 |