Table 3.

Cox proportional hazards model to predict the 5-year mortality of patients with IPF.

Variables	HR	95% CI	p value
Univariate analysis
MMP-7 (continuous)	1.068	1.015–1.124	0.0109
CCL18 (continuous)	1.007	0.999–1.014	0.0734
KL-6 (continuous)	1.001	1.000–1.001	0.0005
SP-A (continuous)	1.006	0.999–1.015	0.1143
SP-D (continuous)	1.000	0.998–1.002	0.9180
Age	1.032	0.982–1.085	0.2128
Sex, M	2.163	0.734–6.370	0.1616
Smoking	1.468	0.546–3.951	0.4471
% VC (continuous)	0.965	0.942–0.989	0.0040
Medication∗	2.730	1.177–6.333	0.0193
Multivariate analysis∗∗
MMP-7 (continuous)	1.074	1.060–1.147	0.0336
KL-6 (continuous)	1.001	1.000–1.002	0.0042
% VC (continuous)	0.981	0.954–1.009	0.1744
Medication∗	2.066	0.667–6.399	0.2086

See legends of Tables 1 and 2 for expansion of abbreviations.

^∗Medication indicates the usage of corticosteroids and/or immunosuppressants.

^∗∗Multivariate Cox analysis was adjusted for age, sex, and smoking history.