Table 4.
SMR for uranium-exposed workers
| Cause of death | Included trials | Participants | Statistical method | SMR (95% CI) | p value |
|---|---|---|---|---|---|
| All malignant neoplasms | 19 | 71,114 | M-H, random effects | 0.90 (0.84 to 0.96) | 0.0009 |
| Lung cancer | 17 | 68,056 | M-H, random effects | 0.95 (0.85 to 1.06) | 0.35 |
| Kidney cancer | 14 | 63,989 | M-H, fixed effect | 0.85 (0.66 to 1.10) | 0.22 |
| Bladder cancer | 13 | 58,359 | M-H, fixed effect | 0.87 (0.69 to 1.10) | 0.24 |
| All lymphatic and hematopoietic tissue neoplasms | 9 | 42,578 | M-H, fixed effect | 0.87 (0.72 to 1.06) | 0.16 |
| Leukemia and aleukemia | 14 | 59,416 | M-H, fixed effect | 0.85 (0.68 to 1.06) | 0.16 |
| Chronic lymphocytic leukemia | 4 | 20,154 | M-H, random effects | 1.00 (0.48 to 2.06) | 0.99 |
| Non-Hodgkin's lymphoma | 15 | 65,951 | M-H, fixed effect | 0.92 (0.73 to 1.15) | 0.45 |
| Hodgkin's lymphoma | 11 | 51,449 | M-H, fixed effect | 1.22 (0.74 to 2.03) | 0.44 |
| Multiple myeloma | 11 | 41,574 | M-H, fixed effect | 1.11 (0.77 to 1.60) | 0.58 |
| Uterine carcinoma | 5 | 2,427 | M-H, fixed effect | 2.00 (0.50 to 7.99) | 0.33 |
| Ovary cancer | 5 | 2,427 | M-H, fixed effect | 0.82 (0.24 to 2.84) | 1 |
| Breast cancer | 7 | 14,631 | M-H, fixed effect | 1.04 (0.59 to 1.86) | 0.88 |
| Prostate cancer | 10 | 45,610 | M-H, fixed effect | 0.88 (0.74 to 1.05) | 0.14 |
| Liver cancer | 9 | 43,854 | M-H, fixed effect | 0.59 (0.42 to 0.81) | 0.001 |
| Central nervous system cancer | 13 | 61,485 | M-H, fixed effect | 1.06 (0.82 to 1.36) | 0.65 |
| Bone cancer | 10 | 49,034 | M-H, fixed effect | 0.77 (0.34 to 1.75) | 0.51 |
| Mesothelioma | 5 | 22,863 | M-H, fixed effect | 1.60 (0.73 to 3.52) | 0.24 |
| Stomach cancer | 14 | 61,450 | M-H, fixed effect | 0.85 (0.72 to 1.01) | 0.07 |
| Pancreas cancer | 13 | 60,356 | M-H, fixed effect | 0.96 (0.80 to 1.16) | 0.7 |
| Esophagus cancer | 12 | 53,597 | M-H, fixed effect | 0.67 (0.51 to 0.88) | 0.004 |
| Colon cancer | 12 | 63,100 | M-H, random effects | 0.77 (0.65 to 0.92) | 0.003 |
| Rectum cancer | 12 | 53,597 | M-H, fixed effect | 0.94 (0.74 to 1.19) | 0.59 |
| Connective tissue cancer | 5 | 33,022 | M-H, fixed effect | 0.83 (0.36 to 1.93) | 0.67 |
| Acute and chronic renal failure | 11 | 50,043 | M-H, fixed effect | 0.87 (0.63 to 1.19) | 0.37 |
| Acute renal failure | 2 | 10,272 | M-H, fixed effect | 0.67 (0.11 to 3.99) | 0.66 |
| Chronic renal failure | 7 | 41,739 | M-H, fixed effect | 0.84 (0.57 to 1.24) | 0.38 |
M-H = Mantel-Haenszel statistics.