Table 1.
Patient characteristics
| Characteristic | n | % |
|---|---|---|
| Age, mean (±SD), year | 57.8 (±11.9) | |
| Sex | ||
| Male | 113 | 68.5 |
| Female | 52 | 31.5 |
| ECOG performance status | ||
| 0 | 37 | 22.4 |
| 1 | 128 | 77.6 |
| Location | ||
| Upper | 10 | 6.1 |
| Middle | 85 | 51.5 |
| Lower | 70 | 42.4 |
| Clinical T stage | ||
| cT3mrf+ | 141 | 85.5 |
| cT4 | 24 | 14.5 |
| Clinical N stage | ||
| cN0 | 15 | 9.1 |
| cN+ | 150 | 90.9 |
| Pathological T stage | ||
| ypT0 | 24 | 14.5 |
| ypT1 | 4 | 2.4 |
| ypT2 | 33 | 20.1 |
| ypT3 | 98 | 59.4 |
| ypT4b | 6 | 3.6 |
| Pathological N stage | ||
| ypN0 | 109 | 66.1 |
| ypN1 | 49 | 29.7 |
| ypN2 | 7 | 4.2 |
| Pathologic CRM | ||
| Negative | 148 | 89.7 |
| Positive | 17 | 10.3 |
| Lymphovascular invasion | ||
| No | 153 | 92.7 |
| Yes | 12 | 7.3 |
| Perineural invasion | ||
| No | 159 | 96.4 |
| Yes | 6 | 3.6 |
| Mucinous component | ||
| No | 143 | 86.7 |
| Yes | 22 | 13.3 |
| Histologic grade | ||
| WD | 25 | 15.2 |
| MD | 129 | 78.2 |
| PD | 6 | 3.6 |
| SRC | 3 | 1.8 |
| Unknown | 2 | 1.2 |
| Tumour regression grade | ||
| TRG 1 | 23 | 13.9 |
| TRG 2 | 43 | 26.1 |
| TRG 3 | 67 | 40.6 |
| TRG 4 | 32 | 19.4 |
| Type of resection | ||
| LAR | 135 | 81.8 |
| APR | 30 | 18.2 |
| Adjuvant chemotherapy | ||
| Administered | 148 | 89.7 |
| Not administered | 17 | 10.3 |
ECOG, Eastern Cooperative Oncology Group; cT3mrf+, mesorectal infiltration with a distance of <2 mm from tumour to mesorectal fascia; CRM, circumferential resection margin; WD, well differentiated; MD, moderately differentiated; PD, poorly differentiated; SRC, signet ring cell carcinoma; TRG, tumour regression grade; LAR, low anterior resection; APR, abdominoperineal resection.