Figure 2.

The organization and governance of the PPMI study and distribution of clinical sites in the United States, Europe and Australia. Data or samples obtained from each PPMI clinical site were transferred to clinical, imaging and biorepository cores, and all data were integrated in the PPMI study database. The PPMI data are publically available through the PPMI website (www.ppmi-info.org). Biological samples, including the longitudinal collection of CSF, blood and urine, were stored at the biorepository and are available to scientists via an application to the review committee through the website [11]. MJFF: Michael J. Fox Foundation, ISAB: Industry Scientific Advisory Board, EAC: External Advisory Committee, CSOC: Clinical Study Oversight Committee, PD: Parkinson’s disease, PPMI: Parkinson Progression Marker Initiative, CSF: cerebrospinal fluid.