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. 2016 May 31;6:26801. doi: 10.1038/srep26801

Table 3. Associations between plasma Aβ levels and composite amyloid PET SUVR.

  All cases Control SCD MCI
Aβ42 r = −0.162, p = 0.003−0.08 (−0.09, −0.07) r = 0.005,p = 0.953 r = −0.189,p = 0.056 r = −0.295, p = 0.002−0.09 (−0.1, −0.06)
Aβ40 r = −0.012, p = 0.828 r = 0.103,p = 0.251 r = 0.014, p = 0.886 r = −0.199, p = 0.035−0.006 (−0.009, −0.004)
Aβ42/Aβ40 r = −0.167, p = 0.002−18 (−27, −10) r = −0.130,p = 0.148 r = −0.205,p = 0.038−33 (−42, −25) r = −0.154, p = 0.105

MCI, mild cognitive impairment; SCD, subjective cognitive decline; PET, positron emission tomography; SUVR, standardized uptake value ratio.

Plasma Aβ were measured using Simoa immunoassay. Associations between plasma Aβ and composite [18F]flutemetamol SUVR were first evaluated with Pearson’s correlation analysis and if significant correlations were found further investigated using RMA adjusting for age and gender. Data are presented as r, p from Pearson’s correlation analysis and slope estimates (95% CI) from RMA; significant results are shown in bold.